The Comprehensive Guide to Kidney Transplantation 2024 Better Results and a New Life for Patients

Kidney Transplant

The Comprehensive Guide to Kidney Transplantation Better Results and a New Life for Patients

What is a Kidney Transplant?

A kidney transplant is a surgical procedure where a healthy kidney from a donor is transplanted into a patient. This procedure is used to treat end-stage renal failure, which means the kidneys do not perform their vital functions sufficiently to support the patient’s life properly.

The procedure requires reliable tissue matching between the donor and recipient kidney, done through a process involving specialized surgeons.

Why Kidney Transplants are Performed?

Kidney transplants are performed to help people with chronic kidney disease or end-stage renal failure. When your kidneys can’t filter toxins properly, you need either dialysis or a kidney transplant.

Kidney Transplant Requirements

Each hospital has its criteria for accepting people as kidney transplant recipients. Generally, candidates should have:

  • End-stage renal failure and be on dialysis.
  • Late-stage chronic kidney disease, approaching the need for dialysis.
  • A life expectancy of at least five years.
  • A full understanding of post-surgery instructions and care.

Best Age for a Kidney Transplant

While most kidney transplant recipients are between 45 and 65 years old, there is no real upper age limit.

However, to ensure the best results, your doctor will likely look for a donor close to your age.

Number of Kidney Transplants a Person Can Have

In some cases, people can undergo two, three, or even four kidney transplants in their lifetime. Your doctor can tell you if this is an option for you.

Contraindications for Kidney Transplantation

Kidney transplants are approved on a case-by-case basis. However, some general factors can make a person ineligible for a kidney transplant, such as:

  • Severe health conditions that make surgery risky.
  • Frequent infections.
  • Short life expectancy.
  • Substance or alcohol abuse.

What Happens During a Kidney Transplant?

The kidney transplant procedure involves placing a healthy kidney in your body, where it can perform all the functions that the failed kidneys cannot. The new kidney is placed in the lower right or left side of your abdomen and is surgically connected to nearby blood vessels.

The vein and artery of the new kidney are attached to your vein and artery, and the ureter of the new kidney is connected to your bladder to allow urine to pass from your body.

What Happens to the Old Kidneys?

In most cases, the surgeon will leave your diseased kidneys inside your body. However, there are three scenarios that may require the removal of your old kidneys:

  • Infection that can spread to the new transplanted kidney.
  • High blood pressure caused by the original kidneys.
  • Reflux or backup of urine into your kidneys.

Duration of Kidney Transplant Surgery

On average, kidney transplant surgery takes two to four hours to complete. The patient is fully anesthetized before the surgery begins. An incision is made in the lower part of one side of the abdomen, and the new kidney is placed in the abdominal area.

The patient can likely get out of bed one day after the surgery and may be able to leave the hospital within a week. If the healthy kidney is obtained from a deceased person, it may take up to a month or more for the new kidney to start functioning properly.

If the healthy kidney is obtained from a living donor, it usually begins to function well within a short period.

Post-Transplant Care

Most people spend about three days in the hospital after a kidney transplant. This allows your medical team to monitor you closely and ensure you are recovering well.

Your new transplanted kidney may start working immediately, or you may need temporary dialysis until it begins to work. You will also need to start taking medications to prevent your immune system from rejecting the new kidney.

After the transplant, the recipient undergoes close monitoring and continuous care to ensure the success of the operation and reduce the chances of complications. Here’s what generally happens after the transplant:

  • Continuous Monitoring: The recipient is placed under continuous monitoring immediately after the transplant. Blood pressure and blood chemistry levels are regularly measured to ensure the stability of the new kidney function.
  • Appropriate Care: The recipient is guided for proper care in the hospital after the transplant, receiving medical support and necessary medications to help prevent the body from rejecting the new kidney.
  • Anti-Rejection Medications: The recipient is prescribed anti-rejection medications to prevent the body from rejecting the transplanted kidney. The recipient must follow a precise schedule for taking these medications regularly, under the guidance of the medical team.
  • Periodic Follow-Up: The recipient needs regular follow-up care and tests to evaluate the function of the transplanted kidney and ensure no complications, such as rejection or infections.
  • Recovery and Rehabilitation: The recipient needs a recovery period after the transplant, which may take several weeks to regain strength and return to normal activity levels.

Kidney Transplant

Benefits of Kidney Transplant

A successful kidney transplant gives you more strength, endurance, and energy. After the transplant, you should be able to return to a more normal lifestyle and have more control over your daily life. You can follow an unrestricted diet and drink fluids freely.

Kidney transplantation is considered a miraculous medical procedure that can change the lives of those suffering from end-stage renal failure. The benefits of this surgical procedure include:

  • Improved Quality of Life: Kidney transplantation restores kidney function for the recipient, allowing them to eliminate many symptoms associated with kidney failure, such as excessive fatigue, high blood pressure, and waste accumulation in the body.
  • Independence from Dialysis: After a kidney transplant, the recipient often no longer needs frequent dialysis sessions, restoring their independence and freedom to organize their lives without the previous restrictions.
  • Improvement in General Health: After the transplant, recipients notice an improvement in overall health, with reduced fatigue and increased activity, enabling them to perform daily activities without difficulty.
  • Increased Survival Chances: Kidney transplantation enhances the survival chances for patients with end-stage renal failure, giving them the opportunity to live a normal and long life.
  • Improved Psychological and Emotional Well-being: Recipients experience an increase in psychological and emotional comfort after the transplant, feeling hopeful and optimistic about their future and the ability to regain a healthy and happy life.

In summary, kidney transplantation is a vital and effective procedure that can provide new life and health to the recipient. These benefits are just the beginning of understanding the comprehensive advantages of this innovative treatment.

Risks of Kidney Transplant

The risks of kidney transplant are the same as those involved in any surgery. There is a risk of bleeding, infection, or breathing problems. You may also experience some side effects from the medications and may be more prone to infections because the medication you will take after the transplant reduces your body’s ability to fight infections.

Organ Rejection

Since your body recognizes the new kidney as a foreign object, it usually tries to get rid of or reject it. However, you will be given medication to prevent rejection.

Due to years of experience, research, and improved anti-rejection medications, kidney transplants are highly successful with few complications after transplantation.

Organ rejection is a condition where the patient’s immune system attacks the transplanted kidney after the transplant procedure. Rejection can occur at different times after transplantation and can be classified into three main patterns:

  1. Hyperacute Rejection: Usually appears within minutes after transplantation and occurs when there is a complete mismatch between the recipient’s and donor’s antigens. Treatment requires immediate removal of the transplanted tissue.
  2. Acute Rejection: Typically occurs within one to three months of transplantation and may respond to increased doses of immunosuppressive medications.
  3. Chronic Rejection: Occurs years after transplantation and results from the gradual immune destruction of the transplanted organ’s tissues.

Rejection is diagnosed through laboratory tests and imaging, and treated by increasing immunosuppressive medications and regular monitoring of kidney functions.

Is Kidney Transplant Better Than Dialysis?

While both options have their pros and cons, kidney transplantation is often the preferred treatment for chronic kidney disease. Kidney transplants generally provide a better quality of life for most people, and studies show that those who undergo successful kidney transplants live longer on average than those who receive dialysis.

Recovery Time After Kidney Transplant

On average, recovery from a kidney transplant takes about six weeks. However, this timeline varies for everyone and depends on your overall health and other factors.

Self-Care During Recovery

It is important to follow any instructions given by the medical team. Here are some general guidelines:

  • Avoid lifting heavy objects and strenuous physical work for at least six to eight weeks after surgery. Do not lift anything heavier than 20 pounds for two to three months, and nothing heavier than 40 pounds for four to six months after surgery.
  • Avoid driving for at least six weeks after surgery. Plan ahead so that a friend or family member can help during this time. Always wear your seatbelt when in a moving vehicle.
  • Engage in simple exercises: Your doctor will recommend starting with stretching and walking exercises. Other excellent exercises include jogging, hiking, cycling, tennis, golf, swimming, and aerobics. All of these can help you regain strength and you can start gradually after the incision heals.

Foods to Avoid After Kidney Transplant

When it comes to the foods and drinks you consume, here are some tips to follow:

  • Drink plenty of water: One key to successful recovery is drinking plenty of water, usually 2 liters (about 68 ounces) daily. It is also good to limit caffeine intake as it is a weak diuretic and contributes to dehydration.
  • Avoid raw or undercooked foods: With a weakened immune system, consuming raw or undercooked foods, especially undercooked meat or eggs, poses a risk of severe illness.
  • Get plenty of protein in your diet: It is important to follow a balanced diet with some special nutritional considerations. Protein is particularly beneficial as it helps you build muscle and regain lost weight. Your provider or dietitian can help you determine how much protein you need each day.

Avoid Grapefruit and Grapefruit Juice: This fruit can cause strong interactions with the medications that suppress your immune system.

Do Not Take Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Some very common over-the-counter medications, including ibuprofen and naproxen, can cause kidney function issues.
You may also want to avoid certain antihistamines and antacids, as these medications and other over-the-counter drugs can sometimes affect other medications or alter absorption.
Speak with your healthcare provider about the safety of these medications and potential alternatives you can try.

Avoid Certain Vitamins and Herbal Supplements: Schisandra, some types of herbal teas, and other natural supplements can interact with transplant medications. You should discuss these supplements with your provider before using them to ensure they are safe.

How Long Can a Person Live with a Kidney Transplant?

People can live many years after receiving a kidney transplant. On average, a kidney from a living donor lasts about 12 to 20 years, while a kidney from a deceased donor lasts about eight to 12 years. Some people undergo more than one kidney transplant in their lifetime.

Can You Live a Normal Life with a Kidney Transplant?

Yes. Many people live healthy and fulfilling lives after a kidney transplant. Currently, the one-year survival rate for kidney transplants is 95%. The average survival rate for three to five years is 90%.

This means that 9 out of 10 people who receive a kidney transplant will still be alive five years after surgery.

Survival rates are estimates and cannot tell you how you will respond to treatment or how long you will live.

When Can I Return to Work After My Kidney Transplant?

Many kidney transplant patients can return to work within a few months after successful surgery. However, various aspects of the recovery process can affect the timing of your return.

You will need to discuss your return to work with your surgeon. When the time approaches, your provider will give you a return-to-work letter.

This will let your employer know when you can start working and what restrictions you have, if any.

When Should You Consult Your Doctor?

After a kidney transplant, you will see your medical team for regular follow-ups.

However, if you experience any of the following symptoms, you should contact your healthcare provider immediately:

  • Fever.
  • New pain around your kidney.
  • Swelling (edema).
  • Flu-like symptoms including chills, headache, dizziness, nausea, or vomiting.
  • A noticeable decrease in the amount of urine you produce.

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